Going Bovine by Libba Bray is the 2010 Printz Award Winner.
Review from School Library Journal: Cameron, a 16-year-old slacker whose somewhat dysfunctional family has just about given up on him, as perhaps he himself has, when his diagnosis of Creutzfeldt-Jacob, "mad cow" disease, reunites them, if too late. The heart of the story, though, is a hallucinatory—or is it?—quest with many parallels to the hopeless but inspirational efforts of Don Quixote, about whom Cameron had been reading before his illness. Just like the crazy—or was he?—Spaniard, Cam is motivated to go on a journey by a sort of Dulcinea. His pink-haired, white-winged version goes by Dulcie and leads him to take up arms against the Dark Wizard and fire giants that attack him intermittently, and to find a missing Dr. X, who can both help save the world and cure him. Cameron's Sancho is a Mexican-American dwarf, game-master hypochondriac he met in the pot smokers' bathroom at school who later turns up as his hospital roommate. Bray blends in a hearty dose of satire on the road trip as Cameron leaves his Texas deathbed—or does he?—to battle evil forces with a legendary jazz horn player, to escape the evil clutches of a happiness cult, to experiment with cloistered scientists trying to solve the mysteries of the universe, and to save a yard gnome embodying a Viking god from the clutches of the materialistic, fame-obsessed MTV-culture clones who shun individual thought. It's a trip worth taking, though meandering and message-driven at times.—Suzanne Gordon, Peachtree Ridge High School, Suwanee, GA END